{"id":396,"date":"2017-04-10T17:00:06","date_gmt":"2017-04-10T15:00:06","guid":{"rendered":"http:\/\/zfbweb.zfb.fuw.edu.pl\/?post_type=portfolio&#038;p=396"},"modified":"2024-05-16T13:01:00","modified_gmt":"2024-05-16T13:01:00","slug":"monte-carlo-simulations-of-cell-response-to-dna-damage-of-various-complexities","status":"publish","type":"portfolio","link":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/portfolio-item\/monte-carlo-simulations-of-cell-response-to-dna-damage-of-various-complexities\/","title":{"rendered":"Monte Carlo simulations of cell response to DNA damage of various complexities"},"content":{"rendered":"<p>DNA is the fundamental molecule encoding and storing the genetic information of all living organisms. DNA damage and repair is by essence a multidisciplinary line of research, and the award of the Nobel Prize of Chemistry in 2015 stresses out the importance of gaining molecular insights into the underlying complex mechanistic pathways. The genetic material is a labile substance that is constantly damaged either spontaneously or due to the action of DNA damaging agents like ionising radiation. Although the damage is efficiently repaired, the DNA repair process is not error free, so that some lesions are misrepaired, leading to genetic modifications called mutations. These lesions can be visualised with the specific repair proteins, which produce the nuclear regions called foci.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DNA is the fundamental molecule encoding and storing the genetic information of all living organisms. DNA damage and repair is by essence a multidisciplinary line of research, and the award of the Nobel Prize of Chemistry in 2015 stresses out<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":3,"featured_media":1759,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"portfolio-types":[16,43,8,74],"class_list":["post-396","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry","portfolio-types-brzozowska","portfolio-types-galecki","portfolio-types-medical-physics","portfolio-types-tartas"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/portfolio\/396","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/types\/portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/comments?post=396"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/media\/1759"}],"wp:attachment":[{"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/media?parent=396"}],"wp:term":[{"taxonomy":"portfolio-types","embeddable":true,"href":"https:\/\/zfbweb.zfb.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/portfolio-types?post=396"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}