Radiobiological laboratory
The Radiobiological Laboratory has been operating since January 2020 and is located in the Department of Biomedical Physics (on the fourth floor). The basic equipment of the laboratory was possible thanks to funding from university funds under the Didactic Innovation Fund.
Contact person:
- dr hab. Beata Brzozowska (p. 4.67)
Lab staff:
- dr Adrianna Tartas (p. 4.58)
- Mateusz Filipek (p. 4.58)
- dr Beata Pszczółkowska (p. 4.58)
Teaching materials for 1st and 2nd degree students of Medical Physics can be found in the following tabs.
DNA repair foci
DNA, which is the fundamental molecule that encodes and stores the genetic information of all living organisms, is also a main target when radiation exposure occurs. Although damage is efficiently repaired, the DNA repair process is not error-free, which means that some lesions are misrepaired, leading to genetic modifications called mutations. Different radiation particles damage a cell in specific ways, giving rise to DSB (double strand breaks) induction. These lesions can be visualized with specific repair proteins, which produce nuclear regions called foci (DNA lesion clusters).
Documents:
- Protocols: cell culture
- Manual of the fluorescent microscope
- Fluorescence of γ-H2AX repair proteins in cells exposed to mixed radiation (version of instruction for remote classes)
- Gamma-H2AX exercise instruction (lab work)
- Image analysis (instruction)